Welcome to our extracellular matrix biology Lab!

The extracellular matrix (ECM) is a customized collection of collagens, glycoproteins, and proteoglycans, that regulates the extracellular microenvironment and functions of each tissue type. We work on 1) the ECM-rich cornea of the eye and corneal diseases like keratoconus, and 2) how specific ECM proteins interact with immune cells and regulate host immunity.

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Shukti Chakravarti, Ph.D.


  • July 10, 2020

    Our manuscript “RNA sequencing of corneas from two keratoconus patient groups identifies potential biomarkers and decreased NRF2-antioxidant responses” by Shinde, Hu and others is now in press in Scientific Reports.

  • July 8, 2020

    Congratulations Carly on your acceptance to Columbia University Medical Center!

  • June 10, 2020

    Our manuscript “Mapping Keratoconus Molecular Substrates by Multiplexed High-Resolution Proteomics of Unpooled Corneas” by Shinde, Hu and others is now in press in OMICS: A Journal of Integrative Biology.