Welcome to our

Extracellular Matrix Biology Lab!

ECM

The extracellular matrix (ECM) is a customized collection of collagens, glycoproteins, and proteoglycans, that regulates the extracellular microenvironment and functions of each tissue type. We work on 1) the ECM-rich cornea of the eye and corneal diseases like keratoconus, and 2) how specific ECM proteins interact with immune cells and regulate host immunity.

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Shukti Chakravarti, Ph.D.

Research

Emerging role of ECM components in immune response and inflammation

News

  • May 17, 2021

    Our manuscript “Pathogenic alleles in microtubule, secretory granule and extra-cellular matrix related genes in familial keratoconus” by Shinde, Sobreira and others is now in press in Human Molecular Genetics.

  • April 26, 2021 

    Maithê Rocha Monteiro de Barros has joined our lab in April 2021! Welcome Maithê!

  • July 10, 2020

    Our manuscript “RNA sequencing of corneas from two keratoconus patient groups identifies potential biomarkers and decreased NRF2-antioxidant responses” by Shinde, Hu and others is now in press in Scientific Reports.