The extracellular matrix (ECM) is a customized collection of collagens, glycoproteins, and proteoglycans, that regulates the extracellular microenvironment and functions of each tissue type. We work on 1) the ECM-rich cornea of the eye and corneal diseases like keratoconus, and 2) how specific ECM proteins interact with immune cells and regulate host immunity.
Shukti Chakravarti, Ph.D.
May 17, 2021
Our manuscript “Pathogenic alleles in microtubule, secretory granule and extra-cellular matrix related genes in familial keratoconus” by Shinde, Sobreira and others is now in press in Human Molecular Genetics.
April 26, 2021
Maithê Rocha Monteiro de Barros has joined our lab in April 2021! Welcome Maithê!
July 10, 2020
Our manuscript “RNA sequencing of corneas from two keratoconus patient groups identifies potential biomarkers and decreased NRF2-antioxidant responses” by Shinde, Hu and others is now in press in Scientific Reports.